High-Quality Ergothioneine(EGT)L-Ergothioneine Anti-Aging Ingredient Manufacturers, Exporter

Product name:Ergothioneine (EGT),L-Ergothioneine
Specification: 99%
CAS No.: 497-30-3
Apperance: white powder
Standard:ISO, USP, Ep
Delivery : EXW,FOB,CFR,CIF,DAP,DDP
Packaging: 1 kgs/bag or customized packaging available
Payment :  T/T bank transfer, Western Union,PayPal
Shelf time:2 years,keep away sunlight, keep dry

Product Description

Product Description
Ergothioneine (EGT, L-Ergothioneine, CAS: 497-30-3) is a rare, naturally occurring sulfur-containing amino acid derived from histidine. It is mainly produced by mushrooms, actinobacteria, and cyanobacteria; humans cannot synthesize it and must obtain it from diet or supplements. As a stable, high-potency antioxidant, it is widely used in cosmetics, food, and health supplements.
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Natural L-isomer by Fermentation

We supply bio-fermented L-Ergothioneine, the biologically active form consistent with substances naturally present in the human body. Free of D-isomer impurities from chemical synthesis. HPLC purity ≥99%, off-white crystalline powder, low impurity, no peculiar odor.

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Excellent Formulation Stability

Water-soluble powder, stable over pH 4-9. Tolerates conventional cosmetic processing temperatures up to 80℃. Not easy to self-oxidize during production and shelf life; no special stabilizer required for water-based formulas.

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Consistent Quality & Documentation

Strict quality control is implemented for every batch. Products are available from stock. Both trial and bulk orders are acceptable. COA, MSDS, and test reports can be provided upon request.

Certificate of Analysis
Physical and Chemical Property
Item Specification Result
Appearance White crystal powder Conforms
Assay ≥99.0% 99.2%
Loss on Drying ≤0.5% 0.087%
Melting point 275°C~277°C 276°C
Optical rotation [a]D≥(+)122° (c=1, H2O) 99.39%
Elemental analysis C: 47.14±0.3%
H: 6.59±0.3%
N: 18.33±0.3%
C: 47.15%
H: 6.71%
N: 18.40%
Solvent residue ≤200ppm 78 ppm
Residue Analysis
Heavy Metals ≤10mg/kg Conforms
Lead (Pb) ≤0.50mg/kg Conforms
Arsenic (As) ≤0.50mg/kg Conforms
Cadmium (Cd) ≤0.50mg/kg Conforms
Mercury (Hg) ≤0.50mg/kg Conforms
Microbiological Tests
Total Plate Count ≤500cfu/g 200cfu/g
Total Yeast & Mold ≤50cfu/g 10cfu/g
E.Coli. Negative/10g Conforms
Salmonella Negative/10g Conforms
S.aureus Negative/10g Conforms
Functions & Applications

💡 Recommended Dosage & Suitability

  • Whitening products: 0.02% to 0.05%
  • Sunscreen products: 0.01% to 0.03%
  • Suitable demographics: Universal (all population groups)
Application of erythrothioneine
1. Unique Natural Antioxidant

Ergothioneine is a highly protective, non-toxic, natural antioxidant that is not easily oxidized in water. This allows it to be present in concentrations up to millimolar levels in certain tissues, actively stimulating cellular antioxidant defense systems.

2. Advanced Skin Protectant

Incorporated into cosmetics for dermatological protection. Sunlight UVA penetrates deeply into the dermis causing cellular senescence and premature photoaging, while UVB triggers direct epidermal harm. Ergothioneine shields cellular structures against broad-spectrum damage.

3. Ophthalmology Applications

Ergothioneine has been discovered to play a crucial role in ocular protection, serving as an active component in development formulas aimed at facilitating eye care and post-operative ophthalmic recovery.

4. Health Supplements & Anti-Aging Formulations

Widely formulated into functional food, nutraceutical beverages, and anti-aging treatments to assist systemic defense mechanisms, cell revitalization, and comprehensive photoprotection.

Packaging & Logistics
Weight Packing Method
1kg 1kg per bag, outer carton box (Double-layered plastic interior + aluminum foil bag seal)
10kgs, 25kg or more Fiber drums or heavy-duty cartons (2-layer protective plastic liner inside)
Packaging display
Weight Bracket Delivery Method Transit Time Service Destination
1kg - 25kgs EMS, DHL, UPS, FedEx 3-7 Business Days Door to door
25kgs - 100kgs DHL, FedEx, Air Freight 3-7 Business Days Door to door / Airport destination
Over 100kgs Air Freight 3-7 Business Days Door to Airport
Sea Cargo 10-35 Business Days Door to Seaport
Frequently Asked Questions (FAQ)
❓ What is the difference between bio-fermentation and chemical synthesis?

Fermented L-Ergothioneine produces the natural biologically active enantiomer, making it the preferred choice for clean-label cosmetics and high-end dietary supplements. In contrast, chemical synthesis frequently produces unwanted D-isomer impurities. Our product is produced via precise bio-fermentation with an HPLC purity of ≥99%.

❓ What are the recommended usage dosages for formulations?

For topical cosmetic skincare (serums, lotions, anti-pollution treatments), recommended incorporation levels are typically 0.01% to 0.2%, with specific whitening formulas utilizing 0.02% to 0.05%. For dietary supplement applications, formulation amounts should align with relevant regional regulatory guidelines.

❓ What are the recommended storage conditions and product shelf-life?

Store in an airtight container in a cool, dry area away from direct sunlight and humidity. In original unopened packaging, the shelf-life is 24 months. Aqueous solutions should ideally be freshly prepared during cosmetic production.

❓ How does L-Ergothioneine maintain formulation stability during heating?

L-Ergothioneine displays superior thermodynamic and chemical stability compared to standard antioxidants. It maintains complete molecular integrity in pH ranges from 4 to 9 and withstands common industrial cosmetic heating processes up to 80°C without requiring specialized chemical stabilizers.

❓ Can regulatory and technical documentation be supplied with batches?

Yes. Every production batch is subjected to comprehensive quality control. We provide Certificate of Analysis (COA), Material Safety Data Sheets (MSDS), microbiological test profiles, and third-party lab analytical reports upon inquiry.

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