Diaminopyrimidine Oxide (trade name Kopexil, CAS 74638-76-9) is a new water-soluble anti-hair-loss active raw material with ≥99% white crystalline powder. Different from traditional hair growth ingredients, it works via dual pathways: it opens follicle potassium channels to boost scalp blood circulation and activate dormant follicles; meanwhile it inhibits collagen fibrosis around hair roots to prevent follicle atrophy, and reduces DHT production to relieve multiple types of alopecia.
Minoxidil is a classic vasodilator. It dilates scalp blood vessels to improve blood circulation around hair follicles, stimulates follicles and prolongs the anagen phase of hair growth. It has a well-documented effect but may cause side effects such as scalp irritation, dryness and itching for some users.
Diaminopyrimidine Oxide is a newer, gentler active. It mainly targets the 5-alpha reductase pathway to reduce DHT accumulation around hair follicles, protecting follicles from DHT damage. It hardly irritates the scalp and does not cause systemic side effects. It is often used in mild anti-hair-loss formulas and can be compounded with minoxidil for synergistic effects.
| Items | Specifications | Results | |
|---|---|---|---|
| Appearance | White to off-white powder | Conforms | |
| Identification | IR | Should be consistent with the reference chart. | Conforms |
| HPLC | The retention time of the main peak of the test solution should be consistent with that of the main peak of the control solution. | Conforms | |
| PH 1% water solution | 6.5-7.5 | 7.0 | |
| Lead | ≤10ppm | Negative | |
| Chromium | ≤2ppm | Negative | |
| Mercury | ≤1ppm | Negative | |
| Cadmium | ≤5ppm | Negative | |
| Total Plate Count | 200 cfu/g | Conforms | |
| Yeast & Mould | 100 cfu/g | Conforms | |
| Coliforms | Negative | Conforms | |
| Salmonella | Negative | Conforms | |
| Pathogenic bacteria | Negative | Conforms | |
| Assay | ≥99.0% | 99.2% | |
As a new anti-hair-loss active ingredient, Diaminopyrimidine Oxide alleviates androgenetic alopecia, postpartum and stress-induced hair shedding. It nourishes hair follicles, strengthens roots and reduces breakage, widely applied in anti-hair loss shampoo, scalp serum, hair tonic, conditioner and scalp spray.
"We added Diaminopyrimidine Oxide into our anti-hair loss scalp serum formula. In our 8-week trial, it effectively reduced scalp DHT levels and helped stabilize hair shedding. The ingredient has low irritation, compatible with mild scalp care formulas. Our end-users appreciate the gentle effect without itching or dryness. It fits perfectly with our clean hair care product positioning."
"As a developer of hair growth products, we were looking for a mild active ingredient to combine with minoxidil. Diaminopyrimidine Oxide works well to protect hair follicles from DHT damage. Its fine powder has good solubility and easy to incorporate into our formulations. Batch consistency is reliable, which greatly simplifies our production schedule."
| Weight | Packing method |
|---|---|
| 1kg | bag/kg, box outside (double plastic bag + Aluminum foil bag inside) |
| 10kgs, 25kg or more | by Drums or carton (2 layers plastic bag inside) |
| Weight | Delivery mothod | Delivery time | Destination |
|---|---|---|---|
| 1kg-25kgs | EMS, DHL, UPS, Fedex | 3-7days | Door to door |
| 25kgs-100kgs | DHL, FedEx, by Air | 3-7days | Door to door (to Airport by Air) |
| more than 100kgs | by Air | 3-7days | Door to Airport |
| by Sea | 10-35days | Door to port |
ShineHerb biotech specializes in the supply of nutritional ingredients, enzymes, plant extracts, vitamins, amino acids, peptides, and other raw materials for global B2B customers. For Diaminopyrimidine Oxide, free samples are available together with documents including COA and MSDS. Please feel free to contact us anytime.