NMN, full chemical name Beta-Nicotinamide Mononucleotide, is a substance naturally present in the human body and participates in the synthesis of NAD+ in cells. NAD+ is the most critical coenzyme in the human body, participating in thousands of biocatalytic reactions and serving as an essential component for biological processes. Vital cellular mechanisms—including metabolism, redox equilibrium, DNA maintenance and repair, gene stability, and epigenetic regulation—fundamentally require the participation of NAD+.
NMN can be naturally biosynthesized in the body and also derived from dietary sources such as broccoli, cabbage, cucumber, edamame, and avocado; however, natural concentrations remain exceedingly low.
Critical NAD+ Depletion: NAD+ levels decrease rapidly with age, with nearly a 50% reduction every 20 years. By age 40, the physiological NAD+ concentration is roughly only 25% of that found in youth.
Dietary Extraction Limits: Due to trace concentrations in natural food, reaching therapeutic quantities solely via diet is impractical. Consuming 300mg of NMN requires ingesting roughly 54 pounds of broccoli or 32 pounds of edamame.
Features direct intestinal absorption pathways, bypassing common rate-limiting digestive bottlenecks.
Actively supports metabolic regulation, blood sugar balance, anti-photoaging for skin, and overall neuronal health.
Highly compatible with Resveratrol and other functional actives for premium complex dietary matrices.
| Product Name | CAS No. |
|---|---|
| NM Nicotinamide | 98-92-0 |
| NMN Nicotinamide mononucleotide | 1094-61-7 |
| NR Nicotinamide Riboside | 1341-23-7 |
| NRC Nicotinamide Riboside Chloride | 23111-00-4 |
| NAD+ Nicotinamide adenine dinucleotide | 53-84-9 |
| NADH Nicotinamide adenine dinucleotide, reduced coenzyme I | 606-68-8 |
| NADP Nicotinamide adenine dinucleotide phosphate | 53-59-8 |
| NMNH β-nicotinamide mononucleotide, reduced form, disodium salt | 108347-85-9 |
Bypasses the bottleneck of the NAMPT rate-limiting enzyme and rapidly replenishes cellular NAD+. NMN enters the bloodstream directly within 10 minutes and is absorbed by internal organs within 30 minutes to facilitate rapid conversion into functional NAD+.
Most oral NR does not convert directly into NMN; rather, it is predominantly digested into NAM, failing to bypass the restriction of the rate-limiting enzyme NAMPT in the salvage synthesis pathway, resulting in limited conversion efficiency.
An essential coenzyme in mitochondria for aerobic oxidation and TCA cycle metabolism generating ATP. However, due to its larger molecular weight, intact exogenous NAD+ struggles to penetrate cell membranes directly, limiting direct cellular uptake.
Shineherb Biotech specializes in the manufacturing, purification, and supply of the entire Nicotinamide series. For inquiries or technical documentation, please contact our support team.
| Test Item | Specification | Analytical Result |
|---|---|---|
| Description | White powder | Conforms |
| Color | White | Conforms |
| Assay | ≥98% | 99.53% (HPLC) |
| Loss on Drying | ≤1% | 0.13% |
| pH Value (100mg/ml in water) | 2.0 ~ 4.0 | 3.0 |
| Mesh Size | 100% pass 80 mesh | Conforms |
| Lead (Pb) | ≤0.5 mg/Kg | Conforms |
| Arsenic (As) | ≤0.5 mg/Kg | Conforms |
| Mercury (Hg) | ≤0.5 mg/Kg | Conforms |
| Chromium (Cr) | ≤0.5 mg/Kg | Conforms |
| Ash Content | ≤5.00% | 2.04% |
| Total Plate Count | ≤1000 cfu/g | Conforms |
| Yeast & Mold | ≤100 cfu/g | Conforms |
| Salmonella | Negative | Negative |
| E. Coli | Negative | Negative |
| Residual Ethanol (GC) | ≤5000 ppm | 100 ppm |
1. Healthcare & Dietary Supplements: NMN powder is widely used as a premium anti-aging bioactive active ingredient to promote cellular energy metabolism and DNA maintenance.
2. Cosmetic Formulations: Niacinamide mononucleotide serves as an advanced functional cosmetic ingredient targeted at anti-photoaging, revitalization, and skin integrity improvement.
| Weight | Packaging Method |
|---|---|
| 1 kg | Aluminum foil bag packaging with double plastic liners inside, packed into an outer box. |
| 10 kg / 25 kg+ | Fiber drums or heavy-duty cartons with double-layer protective food-grade plastic liners inside. |
| Weight Range | Delivery Method | Delivery Time | Destination Type |
|---|---|---|---|
| 1 kg - 25 kg | EMS, DHL, UPS, FedEx Express | 3 - 7 days | Door to door |
| 25 kg - 100 kg | DHL, FedEx, Air Freight | 3 - 7 days | Door to door / Airport destination |
| > 100 kg | Air Freight | 3 - 7 days | Airport destination |
| Sea Freight | 10 - 35 days | Seaport destination |